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Gonadil

Polycystic ovarian syndrome (PCOS) is universally recognized as the commonest endocrinological disorder in women. Initially thought to be  a reproductive disorder, the disorder is more complex, as a number of physiological functions are affected and have a great impact on the health and quality of life of the female. In PCOS, there is an increased androgen [male hormone] synthesis, and disrupted folliculogenesis, irregular menstrual cycles and insulin resistance. In addition to endocrine participation, reproductive and metabolic components also play an active role in PCOS, creating a complex equation to the disorder. The altered metabolic environment, due to PCOS, may have long-term health consequences, leading to chronic conditions such as T2DM and cardiovascular disease.

Altered life-styles, junk food, genetics and a host of other conditions add fuel to the fire and have a physiological impact, in the adolescents and women of child-bearing age with PCOS. The manifestations are manifold and include:

  1. Impaired production of reproductive hormones
  2. Disruption of menstrual cycles
  3.  Reduced rates of fertility and
  4. Ovulation [anovulatory states]
  5. Weight gain
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