Hydroxyprogesterone caproate
HYDROXYPROGESTERONE CAPROATE
Hydroxyprogesterone caproate is a synthetic progestin, also known as 17 hydroxyprogesterone caproate, is closer to progesterone in terms of structure and pharmacology than most other progestins, and is essentially a pure progestogen that is, a selective agonist of the progesterone receptor (PR) with minimal or no other hormonal activity.
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic progestin, also known as 17 hydroxyprogesterone caproate, is closer to progesterone in terms of structure and pharmacology than most other progestins, and is essentially a pure progestogen that is, a selective agonist of the progesterone receptor (PR) with minimal or no other hormonal activity.
However, Hydroxyprogesterone caproate has improved pharmacokinetics compared to progesterone, namely a much longer duration with intramuscular injection in oil solution. Hydroxyprogesterone caproate decreases contractility of the uterine smooth muscle. This effect contributes to prevention of preterm labor. Hydroxyprogesterone caproate is indicated to reduce the risk of preterm birth in women with a singleton pregnancy who have a history of singleton spontaneous preterm birth.
Therapeutic Uses of HPC:
- Reduction in risk of Preterm birth Threatened / Habitual Abortion
- Undiagnosed Vaginal Bleeding
Available Formulations/Strengths:
- Hydroxyprogesterone Caproate: 250mg & 500mg injection in 2ml
Method of Administration:
- Intramuscular injection by registered medical practitioners
DISCLAIMER: Sanzyme is entitled to use the trademark and brand name “GYNONYS” anywhere in the world excluding India. Sanzyme does not intend to market and commercialize GYNONYS in India.
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Since 1969, when we entered into a Joint Venture with Sankyo (now Daiichi-Sankyo) to make gonadotropins to export to Japan, we’ve been at the forefront of biological hormones, and today we have the necessary technological foundation to do path breaking work.